{"id":179,"date":"2015-03-31T12:32:27","date_gmt":"2015-03-31T10:32:27","guid":{"rendered":"http:\/\/new.veterinasmizany.sk\/?page_id=179"},"modified":"2015-05-22T11:33:06","modified_gmt":"2015-05-22T09:33:06","slug":"cea","status":"publish","type":"page","link":"https:\/\/www.chsseychely.sk\/?page_id=179","title":{"rendered":"CEA"},"content":{"rendered":"

CEA (Collie Eye Anomaly)<\/strong><\/p>\n

V\u00a0polovici\u00a0 roku 1980 si chovatelia AUO za\u010dali uvedomova\u0165, \u017ee Collie Eye Anomaly (CEA), je aj u\u00a0AUO jedn\u00fdm z\u00a0faktorov.\u00a0 CEA nie je najv\u00e1\u017enej\u0161\u00edm ani naj\u010dastej\u0161\u00edm o\u010dn\u00fdm ochoren\u00edm u\u00a0AUO, ale zasluhuje si pozornos\u0165 chovate\u013eov, a\u00a0ak je zdiagnostikovan\u00e9 aj \u201epl\u00e1n akcie\u201c.<\/p>\n

Hist\u00f3ria:<\/em><\/p>\n

V\u00a0roku 1980 bolo ve\u013emi m\u00e1lo zn\u00e1me o CEA u\u00a0AUO. Toto ochorenie bolo dobre zdokumentovan\u00e9 u\u00a0k\u00f3li\u00ed, odkia\u013e poch\u00e1dza aj n\u00e1zov, a\u00a0vyskytovalo sa aj u\u00a0\u0161elti\u00ed. Na za\u010diatku si nikto neuvedomoval, \u017ee ochorenie pozorovan\u00e9 u\u00a0AUO je to ist\u00e9, napriek jeho podobe. Ak by ste sa vtedy op\u00fdtali majite\u013eov, chovate\u013eov a\u00a0mnoh\u00fdch veterin\u00e1rnych oftalmol\u00f3gov, ka\u017ed\u00fd by tvrdil: \u201etoto sa u\u00a0V\u00e1\u0161ho plemena sta\u0165 nem\u00f4\u017ee\u201c.<\/p>\n

V\u00a0tom \u010dase sa u\u017e rozv\u00edjalo rozpozn\u00e1vanie medzi chovate\u013emi. ASCA mala u\u017e \u201egenetick\u00fa komisiu\u201c.<\/p>\n

\u0160trukt\u00fara genetickej komisie bola rozdielna oproti teraj\u0161ej, pozost\u00e1vala z\u00a0dvoch \u013eud\u00ed. T\u00ed sa sna\u017eili z\u00edskava\u0165 inform\u00e1cie a\u00a0spr\u00e1vy o\u00a0CEA, ale v\u0161etka dostupn\u00e1 literat\u00fara bola iba o\u00a0k\u00f3li\u00e1ch. Nikto sa nezauj\u00edmal o\u00a0stav u\u00a0AUO. \u00a0Za\u010dali p\u00edsa\u0165 o\u00a0CEA v\u00a0\u010dasopise \u201eAussie Times\u201c, a\u00a0d\u00fafali, \u017ee majitelia postihnut\u00fdch psov sa podelia o\u00a0inform\u00e1cie.<\/p>\n

V\u00a0roku 1984 jedna chovate\u013eka do\u0161la k\u00a0ne\u0161\u0165astn\u00e9mu objavu, \u017ee jej dve \u0161teniatka vo vrhu maj\u00fa CEA. Veterin\u00e1r Alan McMillan zo\u00a0 San Diega, bol oftalmol\u00f3g a\u00a0konzultant ASCA komisie. Chovate\u013eka\u00a0 bola r\u00fdchlo vyh\u013eadan\u00e1, a\u00a0p\u00fdtali sa jej, \u010di si chce \u0161teniatka necha\u0165. Nechcela.\u00a0 \u010clenovia komisie si zobrali\u00a0 dva black tricolor \u0161teniatka a\u00a0dali im men\u00e1 Tweedledee a\u00a0Tweedledum.<\/p>\n

Chovate\u013eka bola ve\u013emi otvoren\u00e1 a\u00a0nap\u00edsala aj kr\u00e1tky \u010dl\u00e1nok do\u201c Aussie Times\u201c o jej sk\u00fasenosti a\u00a0o\u00a0tom \u010do sa stalo. Nane\u0161\u0165astie to spustilo negat\u00edvne reakcie od jej kamar\u00e1tov, ktor\u00e9 boli pozorovan\u00e9 ned\u00e1vno v\u00a0spojitosti s\u00a0epilepsiou. Jeden \u010dlovek nap\u00edsal do Times, kde odporu\u010dil chovate\u013eke vykastrova\u0165 jej \u201ecarrier\u201c chovn\u00e9ho psa, nazna\u010duj\u00fac \u017ee bola krut\u00e1 lie\u010di\u0165 toho psa touto cestou.<\/p>\n

Medzit\u00fdm komisia z\u00edskala dostatok inform\u00e1ci\u00ed, aby do\u0161la k\u00a0z\u00e1veru, \u017ee CEA u AUO je pravdepodobne reces\u00edvne, tak ako u\u00a0k\u00f3li\u00ed a\u00a0\u0161elti\u00ed. Na potvrdenie tejto inform\u00e1cie, do\u0161lo ku kr\u00ed\u017eenia Dee a\u00a0Dum, ke\u010f boli dostato\u010dne star\u00ed. V\u0161etky \u0161teniatka boli postihnut\u00e9, \u010do potvrdilo z\u00e1ver, \u017ee CEA u\u00a0AUO je reces\u00edvne.<\/p>\n

\u010ealej sa robili \u010fal\u0161ie kr\u00ed\u017eenia.\u00a0 Po zozbieran\u00ed v\u0161etk\u00fdch inform\u00e1ci\u00ed, bolo potvrden\u00e9 \u017ee CEA u\u00a0AUO je reces\u00edvne dedi\u010dn\u00e9 tak ako u\u00a0k\u00f3li\u00ed a\u00a0\u0161elti\u00ed. Na z\u00e1ver bol publikovan\u00fd \u010dl\u00e1nok Rubinom, Nelsonom a Sharpom \u201e Collie Eye Anomaly in Australian Shepherd dogs\u201c v\u00a0Journal of Veterinary and Comparative Ophtalmology.<\/p>\n

Mana\u017ement CEA kr\u00edzy:<\/em><\/p>\n

CEA bolo v\u00a0roku 1908 relat\u00edvne \u010dast\u00e9, mo\u017eno a\u017e \u010dastej\u0161ie ako in\u00e9 o\u010dn\u00e9 katarakty. Celkov\u00e9 zistenie, \u017ee CEA je reces\u00edvne pomohlo chovate\u013eom bojova\u0165 s\u00a0t\u00fdm, napriek tomu, \u017ee mnoh\u00e9 inform\u00e1cie boli r\u00f4znymi chovate\u013emi zatajovan\u00e9.<\/p>\n

Na pomoc vo vzdel\u00e1van\u00ed\u00a0 chovate\u013eov, bola vypracovan\u00e1 jednostranov\u00e1 informa\u010dn\u00e1 bro\u017e\u00fara pod\u013ea vzoru Morris Animal Foundation pre Kombinovan\u00e9 Imunodeficientne ochorenia u\u00a0Arabsk\u00fdch kon\u00ed. \u00a0\u00a0MAF v\u00fdrazne podporovalo\u00a0 vydanie tejto bro\u017e\u00fary. \u00a0Chovate\u013esk\u00fd program, mana\u017ement reces\u00edvnych ochoren\u00ed, ktor\u00e9 sa daj\u00fa identifikova\u0165 u\u00a0ve\u013emi mlad\u00fdch zvierat je z\u00e1kladom, bez oh\u013eadu na druh.<\/p>\n

V\u00a0roku 1990 sa za\u010dala vypracov\u00e1va\u0165 anal\u00fdza rodokme\u0148ov pre CEA. Boli pou\u017eit\u00e9 \u00fadaje z\u00a0v\u00fdskumu, a\u00a0\u010fal\u0161ie inform\u00e1cie, ktor\u00e9 sa \u0161\u00edrili medzi chovate\u013emi. Bola pou\u017eit\u00e1 CEA bro\u017e\u00fara ako podklad pre v\u00fdsledky anal\u00fdzy.\u00a0 Organizovali sa semin\u00e1re\u00a0 a\u00a0vzdel\u00e1vali sa chovatelia.<\/p>\n

Medzit\u00fdm chovatelia zo severnej Kalifornie, bojuj\u00faci s\u00a0CEA v\u00a0ich l\u00edni\u00e1ch dospeli k\u00a0z\u00e1veru, \u017ee treba nie\u010do urobi\u0165.\u00a0 Vznikol testovac\u00ed chovate\u013esk\u00fd program. \u00a0Vymysleli v\u00fdborn\u00fd s\u00fabor formul\u00e1rov na dokument\u00e1ciu chovu, vrhu ako tak\u00e9ho a v\u00fdsledky vy\u0161etren\u00ed \u0161teniat. T\u00edto chovatelia to za\u010dali aj publikova\u0165.<\/p>\n

Z\u00edskali pln\u00fa stranu v\u00a0Aussie Times, podp\u00edsan\u00fa nimi v\u0161etk\u00fdmi s\u00a0titulkom \u201e For Your Eyes Only\u201c. Hromadne priznali, \u017ee produkovali CEA a\u00a0pridali zoznam s\u00a0menami ich psov \u2013 pren\u00e1\u0161a\u010dov. Odozva v\u0161ak nebola tak\u00e1 ako u\u00a0chovate\u013eky Dee a\u00a0Dum. Nakoniec sa dohodli na testovan\u00ed chovn\u00fdch jedincov aby \u201evy\u010distili\u201c chov.<\/p>\n

V\u00a0roku 1990 bol objaven\u00fd g\u00e9n k\u00f3duj\u00faci CEA.<\/p>\n

Chovate\u013esk\u00fd mana\u017ement CEA:<\/em><\/p>\n

Dobr\u00e1 spr\u00e1va je \u017ee CEA, u\u017e nie je \u010dast\u00e9 u\u00a0AUO. Menej ako pol percenta psov je postihnut\u00fdch, \u010do nazna\u010duje, \u017ee okolo 5% s\u00fa pren\u00e1\u0161a\u010di. To v\u0161ak st\u00e1le znamen\u00e1, \u017ee jeden z\u00a020 psov m\u00e1 aspo\u0148 jednu k\u00f3piu g\u00e9nu s\u00a0mut\u00e1ciou. Je to st\u00e1le dos\u0165 na to, aby si na to chovatelia d\u00e1vali pozor. S\u00a0t\u00fdmito \u010d\u00edslami, je DNA testovanie ka\u017ed\u00e9ho jedinca nevyhnutn\u00e9.\u00a0 Spoznanie ochorenia, zau\u017e\u00edvanie si \u00a0DNA testovania a\u00a0tradi\u010dn\u00fdch o\u010dn\u00fdch vy\u0161etren\u00ed, je nevyhnutn\u00e9 na efekt\u00edvny \u201eboj\u201c s\u00a0CEA v\u00a0chovate\u013esk\u00fdch programoch. S\u00a0trochou \u00fasilia m\u00f4\u017eeme frekvenciu mut\u00e1cie zn\u00ed\u017ei\u0165 e\u0161te viac.<\/p>\n

CEA je pr\u00edtomn\u00e9 u\u017e pri naroden\u00ed, tak\u017ee postihnut\u00e9 \u0161te\u0148at\u00e1 s\u00fa identifikovan\u00e9 u\u017e po\u010das o\u010dn\u00e9ho vy\u0161etrenia \u0161teniat. Je d\u00f4le\u017eit\u00e9 vy\u0161etrova\u0165 v\u0161etky \u0161te\u0148at\u00e1. Typick\u00e9 je, \u017ee jedno zo \u0161tyroch \u0161teniat v\u00a0postihnutom vrhu m\u00e1 CEA. Ak sa vy\u0161etria len \u0161te\u0148at\u00e1, ktor\u00e9 id\u00fa na chov, postihnut\u00e9 \u0161te\u0148a m\u00f4\u017ee osta\u0165 neidentifikovan\u00e9. Dve tretiny z\u00a0norm\u00e1lneho kr\u00ed\u017eenia bud\u00fa pren\u00e1\u0161a\u010di, tak\u017ee je ve\u013emi d\u00f4le\u017eit\u00e9 vedie\u0165 \u010di je\u00a0 alebo nie je CEA pr\u00edtomn\u00e9 vo vrhu.<\/p>\n

Choroid\u00e1lna hypopl\u00e1zia (CH), je naj\u010dastej\u0161\u00ed defekt, ktor\u00fd je pr\u00edtomn\u00fd u\u00a0postihnut\u00fdch psov.\u00a0 V\u00e4\u010d\u0161ina nem\u00e1 v\u00e1\u017eny kolob\u00f3m optick\u00e9ho nervu alebo po\u0161kodenie sietnice.\u00a0 \u0160te\u0148at\u00e1 by mali by\u0165 vy\u0161etren\u00e9 v\u00a0\u010do najni\u017e\u0161om veku, lebo CH nemus\u00ed byt vidite\u013en\u00e9 pre vy\u0161etruj\u00faceho ke\u010f sa tapet\u00e1lny pigment vypln\u00ed.\u00a0 T\u00fdm m\u00f4\u017ee d\u00f4js\u0165 k\u00a0vzniku \u201e maskovan\u00fdch postihnut\u00fdch\u201c. Preto by mali chovatelia vyvin\u00fa\u0165 \u00faplne maxim\u00e1lne \u00fasilie na vy\u0161etrenie \u0161teniat vo veku 5 \u2013 7 t\u00fd\u017ed\u0148ov.\u00a0 Ak by to bolo nesk\u00f4r, je ve\u013ek\u00e9 riziko \u017ee postihnut\u00e9 \u0161te\u0148at\u00e1 nebud\u00fa zdiagnostikovan\u00e9.<\/p>\n

Ak m\u00e1 pes CEA, obaja rodi\u010dia s\u00fa pren\u00e1\u0161a\u010di. \u00a0Tam nie je d\u00f4vod ich DNA testova\u0165. Star\u00ed rodi\u010dia, zdrav\u00ed pln\u00ed a\u00a0polovi\u010dn\u00ed s\u00farodenci postihnut\u00e9ho psa, a\u00a0pln\u00ed s\u00farodenci rodi\u010dov by mali by\u0165 otestovan\u00ed, aby bolo zrejm\u00e9 \u010di m\u00f4\u017ee by\u0165 pou\u017eit\u00fd v\u00a0chove v\u00a0s\u00favislosti s\u00a0CEA. Nechovn\u00ed psi, nevy\u017eaduj\u00fa DNA testovanie ( z\u00a0h\u013eadiska chovu). \u00a0Ak sa n\u00e1jde CEA mut\u00e1cia u\u00a0pr\u00edbuzn\u00fdch , ich prvostup\u0148ov\u00ed pr\u00edbuzn\u00ed (rodi\u010dia, potomstvo, pln\u00ed s\u00farodenci) by mali by\u0165 otestovan\u00ed aby sa pos\u00fadilo ich zaradenie do chovu. Rodi\u010dia CEA \u0161te\u0148a\u0165a a\u00a0ak\u00fdko\u013evek pes, ktor\u00fd je DNA otestovan\u00fd ako pren\u00e1\u0161a\u010d, m\u00f4\u017ee by\u0165 kr\u00ed\u017een\u00fd len s\u00a0geneticky otestovan\u00fdm \u201eclear\u201c jedincom. Ide\u00e1lne ka\u017ed\u00fd kryc\u00ed pes by mal by\u0165 otestovan\u00fd, bez oh\u013eadu na to, \u017ee rodi\u010dia boli otestovan\u00fd ako \u201eclear\u201c.<\/p>\n

DNA test m\u00f4\u017ee by\u0165 pou\u017eit\u00fd aj na potvrdenie, alebo vyvr\u00e1tenie v\u00fdsledku be\u017en\u00e9ho o\u010dn\u00e9ho vy\u0161etrenia. \u00a0Veterin\u00e1rny oftalmol\u00f3govia s\u00fa vysoko \u0161pecializovan\u00ed , ale ak\u00e9ko\u013evek fyzick\u00e9 vy\u0161etrenie je prirodzene subjekt\u00edvne.<\/p>\n

Zdroj: \u00a0www.ASHGI.org<\/a><\/p>\n

Vo\u013en\u00fd preklad: MVDr. Krist\u00edna Kova\u013eov\u00e1<\/p>\n","protected":false},"excerpt":{"rendered":"

CEA (Collie Eye Anomaly) V\u00a0polovici\u00a0 roku 1980 si chovatelia AUO za\u010dali uvedomova\u0165, \u017ee Collie Eye Anomaly (CEA), je aj u\u00a0AUO jedn\u00fdm z\u00a0faktorov.\u00a0 CEA nie je najv\u00e1\u017enej\u0161\u00edm ani naj\u010dastej\u0161\u00edm o\u010dn\u00fdm ochoren\u00edm u\u00a0AUO, ale zasluhuje si pozornos\u0165 chovate\u013eov, a\u00a0ak je zdiagnostikovan\u00e9 aj…Read More…<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-179","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.chsseychely.sk\/index.php?rest_route=\/wp\/v2\/pages\/179","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.chsseychely.sk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.chsseychely.sk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.chsseychely.sk\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.chsseychely.sk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=179"}],"version-history":[{"count":2,"href":"https:\/\/www.chsseychely.sk\/index.php?rest_route=\/wp\/v2\/pages\/179\/revisions"}],"predecessor-version":[{"id":278,"href":"https:\/\/www.chsseychely.sk\/index.php?rest_route=\/wp\/v2\/pages\/179\/revisions\/278"}],"wp:attachment":[{"href":"https:\/\/www.chsseychely.sk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=179"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}